Cabergoline Information

Treating disorders associated with high levels of the hormone prolactin, either due to tumors in the pituitary gland or to unknown causes. It may also be used for other conditions as determined by your doctor also Cabergoline is a dopamine receptor agonist. It works by blocking prolactin secretion from the pituitary gland.

Do NOT use cabergoline if:

  • you are allergic to any ingredient in cabergoline or to ergot derivatives (eg, ergotamine)
  • you have uncontrolled high blood pressure
  • you have a history of heart valve problems or certain fibrotic (scarring) disorders (eg, of the lung, heart, kidneys)
  • you are taking a butyrophenone (eg, haloperidol), metoclopramide, a phenothiazine (eg, chlorpromazine), or a thioxanthene (eg, thiothixene)
  • you have taken or will be taking a “triptan” (eg, sumatriptan) within 24 hours before or after taking cabergoline
  • Contact your doctor or health care provider right away if any of these apply to you.

Before using cabergoline:

Some medical conditions may interact with cabergoline. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver problems or high blood pressure
  • if you have developed high blood pressure caused by pregnancy

if you take any medicine that may lower blood pressure or cause heart valve problems. Check with your doctor or pharmacist if you are unsure if any of your medicines may lower blood pressure or cause heart valve problems

Some MEDICINES MAY INTERACT with cabergoline. Tell your health care provider if you are taking any other medicines, especially any of the following:

Macrolides (eg, clarithromycin) because they may increase the risk of cabergoline’s side effects

Butyrophenones (eg, haloperidol), metoclopramide, phenothiazines (eg, chlorpromazine), or thioxanthenes (eg, thiothixene) because they may decrease cabergoline’s effectiveness

“Triptans” (eg, sumatriptan) because the risk of their side effects may be increased by cabergoline

This may not be a complete list of all interactions that may occur. Ask your health care provider if cabergoline may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use cabergoline:

Use cabergoline as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take cabergoline by mouth with or without food.

It may be helpful to mark on a calendar which days you are supposed to take cabergoline.

If you miss a dose of cabergoline, contact your doctor right away.

Ask your health care provider any questions you may have about how to use cabergoline.

Important safety information:

Cabergoline may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use cabergoline with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Cabergoline may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

Some patients taking cabergoline have developed certain behavioral changes (eg, increased gambling or sexual urges). These effects usually go away when treatment with cabergoline is stopped. Contact your doctor right away if you notice any unusual behavioral changes.

If you think you may be pregnant, contact your doctor so that a pregnancy test can be arranged.

Lab tests, including chest x-rays, blood prolactin levels, and heart and kidney function, may be performed while you use cabergoline. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

Cabergoline should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using cabergoline while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking cabergoline.

How to take cabergoline

Before you start the treatment, read the manufacturer’s printed information leaflet from inside the pack. It will give you more information about cabergoline and will provide you with a full list of the side-effects which you may experience from taking it.

The dose you will need to take will depend upon the reason you are taking cabergoline. You may be asked to take cabergoline just for a few days if it is to stop breast milk; or each day if you have Parkinson’s disease; or, if you are taking cabergoline to reduce high prolactin levels, you may only need one dose a week. Your doctor will tell you how much to take and how often to take it, and this information will also be printed on the label of the pack to remind you. Read the directions from your doctor carefully and take cabergoline exactly as you are told to. If you are taking cabergoline for the first time, your doctor may give you a small dose and then gradually increase your dose. Slowly increasing your dose like this will help to reduce side-effects, such as dizziness, which can occur during the first few days of treatment.

Swallow the tablet with a drink of water, at a mealtime. Taking cabergoline with a meal will help to reduce the risk of feeling sick (nausea).

Try to take cabergoline at the same time(s) of day each day; if you are taking it weekly, take it on the same day of the week each week.

If you forget to take a dose, take it as soon as you remember. If when you remember, it is nearly time for your next dose then take your next dose when it is due but leave out the missed dose. Do not take two doses together to make up for a forgotten dose

Getting the most from your treatment

Try to keep your regular appointments with your doctor so your progress can be checked. Cabergoline can cause heart and lung problems, particularly in people who need to take it over a long period of time. In order for your doctor to check for this, you may need to have an ECG, lung function tests, blood tests and an X-ray from time to time if you are taking cabergoline long-term.

There are two different brands and several different strengths of cabergoline tablets. Each time you collect a fresh supply of tablets, it’s a good idea to check the packet to make sure they are what you are expecting. If you have any questions about your tablets, ask your pharmacist for advice.

If you are a woman, you may want to discuss what forms of contraception are suitable for you. Hormonal forms of contraception (such as ‘the pill’) may not be suitable while you are taking cabergoline.

Sometimes people taking cabergoline can fall asleep suddenly with little or no warning of being tired beforehand. Until you know how you react, take extra care if you drive or operate machinery. If you do find yourself falling asleep suddenly, you should see your doctor as soon as possible for advice, and avoid driving or using tools and machines in the meantime.

Treatment with medicines like cabergoline can sometimes cause problems with impulsive types of behaviour. If you notice any changes in your behaviour, such as an increased desire to gamble, binge eat, or spend excessively, or an increased sex drive, you must let your doctor know as soon as possible.

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