Femcinol gel

What is Femcinol A?

Femcinol A Gel is a medicine that is used for the treatment of Bacterial infections of skin, Bacterial infections of lungs, Bacterial infections of internal organs, Bacterial infections of female reproductive organs, Bacterial infections of soft tissue, Bacterial infections of dental and other conditions.

Femcinol A Gel contains Clindamycin, and Nicotinamide as active ingredients.

Femcinol A Gel works by inhibiting the growth of bacteria; helping tissue in respiration and metabolism of fats, protein thus lowers blood cholesterol by inhibiting the synthesis of LDl.

How it works

Clindamycin belongs to a class of medications called as lincomycin antibiotics. It inhibits the synthesis of essential bacterial proteins thereby stopping bacterial growth. In case of acne, in addition to killing of bacteria, clindamycin prevents spread of infection by reducing the free fatty acids on the skin surface that clog the pores of skin and promote overgrowth of bacteria.

Nicotinamide is an amide form of nicotinic acid. Nicotinamide is a component of two coenzymes, which help in tissue respiration and metabolism of  lipids, amino acids, proteins, and purines. Nicotinamide lowers blood cholesterol and triglyceride levels by inhibiting the synthesis of very low density lipoproteins.

Clindamycin Phosphate :-         

Clindamycin Inhibits Protein Synthesis Of Bacteria By Binding To The 50S Ribosomal Subunits Of The Bacteria. Specifically, It Binds Primarily To The 23S RNA Subunit. Topical Clindamycin Reduces Free Fatty Acid Concentrations On The Skin And Suppresses The Growth Of Propionibacterium Acnes (Corynebacterium Acnes) , An Anaerobe Found In Sebaceous Glands And Follicles

Nicotinamide :-     

Nicotinamide Is A Component Of Two Coenzymes, Which Bring About Tissue Respiration, Lipid, Amino Acid, Protein, And Purine Metabolism. Nicotinamide Lowers Blood Cholesterol And Triglyceride Levels By Inhibiting The Synthesis Of Very Low Density Lipoproteins.


Adult: PO Serious anaerobic infections 150-300 mg 6 hrly, up to 450 mg 6 hrly for severe infections. Max: 1.8 g/day. Prophylaxis of endocarditis 600 mg 1 hr before dental procedure. IV Serious anaerobic infections 0.6-2.7 g/day in divided does, up to 4.8 g/day for severe infections. Toxic shock syndrome W/ penicillin G or ceftriaxone: 900 mg 8 hrly. Pelvic inflammatory disease W/ gentamicin: 900 mg 8 hrly. Vaginal Bacterial vaginosis As pessary or 2% cream: 100 mg/day at night for 3-7 days. Topical Acne As 1% preparation: Apply twice daily.

Nicotinamide is used in the treatment of nutritional deficiencies.

Clindamycin Topical is used in the treatment of acne (pimples).

Clindamycin Phosphate :-

Acne Vulgaris, Babesiosis, Bacterial Infections, Bacterial Vaginosis, Dental Infections, Endocarditis, Hidradenitis Suppurativa, Intra-abdominal Infections, Malaria, Osteomyelitis, Pelvic Infections, Peritonitis, Pulmonary Infection, Septic Arthritis, Septicaemia.

Nicotinamide :-

To Treat Inflammatory Skin Disease Like Acne, Anxiety And Alzheimer’s Disease.

——Side Effects——

Diarrhoea, nausea, vomiting, abdominal pain; erythema multiforme, contact dermatitis, exfoliative and vesiculous dermatitis, urticaria; eosinophilia; local irritation, thrombophloebitis. Potentially Fatal: Gasping syndrome (neonates); pseudomembranous colitis

—Side-effects of Femcinol Adp?—-

Elevated SGPT & SGOT, elevated alkaline phosphatase concentration, esophageal ulceration, pseudomembranous colitis, cardiac arrest, colonic ulceration, nausea, vomiting, abdominal pain, rashes, vaginitis, contact dermatitis.

Burning sensation, Application site irritation, Dry skin, Itching, Application site redness of skin.

Rash, Abnormal liver function tests, Allergic sensitization, Blurred vision, Diarrhoea, Dizziness, Flushing, Gastrointestinal discomfort, Vomiting, Nausea, Headache, Liver toxicity, Increased glucose level in blood.

The most commonly reported side-effects of Femcinol Adp Gel are Skin irritation, Dry skin, Sunburn, Skin burning sensations, Skin redness, and Skin discomfort.

The following is a list of possible side effects that may occur from the use of Femcinol Adp Gel. This is not a comprehensive list. These side effects are possible, but do not always occur. Some of the side effects may be rare but serious. Consult your doctor if you observe any of the following side effects, especially if they do not go away.

  • Skin irritation
  • Dry skin
  • Sunburn
  • Skin burning sensations
  • Skin redness
  • Skin discomfort
  • Skin itching
  • Skin exfoliation
  • Acne
  • Erythema
  • Scaling
  • Pruritus
  • Burning
  • Fast heartbeat
  • Puffiness or swelling of the eyelids or around the eyes
  • Ulcers
  • Peeling
  • Joint or muscle pain
  • Face
  • Sore throat
  • Cough or hoarseness
  • Shortness of breath
  • Blurred vision
  • Sores
  • Nausea
  • Skin rash
  • White spots in the mouth or on the lips
  • Blistering
  • Red or yellow eyes or skin
  • Hives or welts
  • Heartburn
  • Chills
  • Vomiting
  • Thrush
  • Itching
  • Unusual weight loss
  • Bleeding gums
  • Loss of appetite
  • Unusual tiredness.
  • Diarrhea
  • Dizziness
  • Difficulty with swallowing
  • Chest pain
  • Scaly skin or lips
  • Dry mouth
  • Loosening of the skin
  • Stomach cramps
  • Headache
  • Abdominal pain

Clindamycin Phosphate :-         

Elevated SGPT & SGOT, Elevated Alkaline Phosphatase Concentration, Esophageal Ulceration, Severe Diarrhea, Ventricular Fibrillation, Anaphylactic Shock, Pseudomembranous Colitis, Cardiac Arrest, Colonic Ulceration, Mucosal Edema, Nausea, Vomiting, Abdominal Pain, Rashes, Vaginitis, Contact Dermatitis, Leukocytoclastic Angiitis, Local Irritation.

Nicotinamide :-     

Hepatotoxicity, Cholestasis, Portal Fibrosis, Headache, Fatigue, Urge To Vomit (nausea), Stomach Upset, Dizziness, Dry Hair, Diarrhea, Blurred Vision, Flushing And Rash.

—–Femcinol A Gel Working, Mechanism of Action and Pharmacology—-


Femcinol A Gel improves the patient’s condition by performing the following functions:

Inhibiting the growth of bacteria.

Helping tissue in respiration and metabolism of fats, protein thus lowers blood cholesterol by inhibiting the synthesis of LDL.

——Femcinol A Gel Precautions——


Before using this drug, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

  • Be careful if you are on birth control pills
  • Consult your doctor if you have asthma, eczema, kidney or liver disease
  • Do not consume if allergic to any ingredient in the medicine
  • Do not consume if pregnant or breastfeeding
  • Do not use the medicine if suffering from renal or hepatic impairment
  • Take caution if you are having allergic reactions.

Renal and hepatic diseases; pregnancy and lactation; GI disease; elderly, females, neonates, atopic patients. Regular monitoring of blood counts, liver and kidney functions.

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

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