Loceryl Cream (Amorolfine 2.5%)
What is Amorolfine for:
Amorolfine is used to treat certain fungal infections of the skin (e.g. athlete?s foot). It is a topical antimycotic, sometimes known as an antifungal. It is used to kill a wide variety of fungi that can cause nail infections.
How does Amorolfine work:
Amorolfine kills fungi and yeasts by interfering with their cell membranes. It works by stopping fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol disrupts the cell membrane. The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As amorolfine disrupts the cell membranes, it kills the fungal cells.
How should Amorolfine be used:
Always use amorolfine exactly as your doctor or pharmacist has instructed you .
Apply the medicated Cream to infected nails 1?2 times a week. Firstly file the infected areas of the nail, including the nail surface. Then use an alcohol swab, or nail varnish remover, to clean the nail surface. Treat the nail by applying the Cream evenly over the entire surface. Allow the treated nail(s) to dry for approximately 3 minutes. Finger nails should be treated for 6 months and toenails for 9?12 months, with a review every 3 months. Dosage will also depend on your age, gender, medical condition, response to therapy, and use of certain interacting medicines.
Common side effects of Amorolfine :
Nail becoming discoloured, loose or starting to separate from the nail bed, Burning sensation or allergic skin reaction (contact dermatitis). A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling(especially of the face/tongue/throat),dizziness, trouble breathing
What do I do if I miss a dose
Do not worry if you forget to use your medication at the right time. When you remember, start using the product again, in the same way as before. Do not double the dose to catch up.
What precautions should I take when taking Amorolfine :
Before taking amorolfine, tell your doctor or pharmacist if you are allergic to it; or to other antifungals; or if you have any other allergies.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist in case of:
Allergic (hypersensitive) to amorolfine or any of the other ingredients
pregnant or planning to become pregnant
Before using this medication tell your doctor or pharmacist your medical history, especially any of the following:
a weak immune system
poor circulation in your hands and feet
severely damaged or infected nails
Before having surgery, tell your doctor or dentist that you are taking this medication.
Alcohol intake is not known to affect amorolfine.
Amorolfine can be used in the elderly
It should not be used in case ofchildren under 12 years of age
Avoid nail varnish or artificial nails during treatment of the nails.
Do not get amorolfine in your eyes or ears, if you do wash it out with water immediately and contact your doctor, pharmacist or nearest hospital straight away.
Avoid the medicine coming into contact with mucous membranes (e.g.mouth and nostrils).
Do not inhale.
Always complete the full course.
Can I take Amorolfine with other medicines:
Use of nail varnish or artificial nails should be avoided during treatment.
How do I store Amorolfine :
Keep all medicines out of the reach and sight of children.
Store in a cool, dry place, away from direct heat and light. Store below 30°C.
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Topical Antifungals & Antiparasites.