Tretizen 20 Information

Tretizen 20 mg Capsules (Isotretinoin) – Product Information

Isotretinoin Capsules (Tretizen 20 mg), is an extremely powerful and potent acne-controlling medicine, is used to treat severe recalcitrant nodular acne which are resistant to therapy, particularly cystic acne and acne conglobata, especially when the lesions involve the trunk. Nodules are inflammatory lesions which have a diameter of 5 mm or greater. “Severe,” by definition, means “many” as opposed to “few or several” nodules.

A single course of Tretizen 20 mg therapy for 15 to 20 weeks has been shown to result in total and prolonged remission of disease in many patients. If a second course of therapy is required, it should not be started until at least 8 weeks after completion of the first course of the medication.

Tretizen 20 mg Capsules (Isotretinoin) manufactured by Zen Lab are available in in the strengths of 5 mg, 10 mg and 20 mg.

Active Ingredient

The active ingredient present in Tretizen 20 mg capsules is Isotretinoin. Each soft gel capsule contains 5 mg of the active ingredient Isotretinoin.

How Does Isotretinoin (Tretizen 20 mg Capsules) Work?

Isotretinoin (Tretizen 20 mg Capsules) work by cutting down the amount of oily substances (sebum) made by the glands in your skin. Tretizen 20 mg capsules (Isotretinoin) will also assist in reducing the bacteria, inflammation and open clogged pores.

Uses of Isotretinoin (Tretizen 20 mg)

Isotretinoin (Isotretinoin) is used to treat severe nodular acne. It is usually given after other types of acne medications or antibiotics have been tried without successful treatment of symptoms.

Tretizen 20 mg capsules by Zen Lab (Isotretinoin, Isotretinoin) is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly. It may also be used to treat other skin diseases as determined by your doctor including:

  • folliculitis, gram-negative (bacterial infection of the skin on the face beginning near the nose)
  • hidradenitis suppurativa (sweat gland problem)
  • rosacea (red skin disorder of the face, usually of the nose and cheeks)
  • thickened or patchy skin disorders, such as keratosis follicularis, palmoplantar keratoderma, lamellar ichthyosis, or pityriasis rubra pilaris.

We supply Tretizen 20 mg. Each soft gel Tretizen 20 mg capsule contains 5 mg, 10 mg or 20 mg of Isotretinoin. It is also known as Isotretinoin and Isotretinoin.

How to Use Tretizen 20 mg Capsules

  • Take Tretizen 20 mg (Isotretinoin, Isotretinoin) exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended.
  • Always take Tretizen 20 mg (Isotretinoin) with a full glass of water to prevent the capsule from melting in your esophagus (food pipe), causing irritation. Do not chew or suck on the capsule. Swallow it as quickly as possible.
  • Your acne may seem to get worse at first, but should then begin to improve.
  • To be sure Tretizen 20 mg capsules (Generic Isotretinoin) are not causing harmful effects, your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.
  • Never share Tretizen 20 mg (Isotretinoin) with another person even if they have the same symptoms you have.

 

Tretizen 20 mg Capsules During Breastfeeding

It is not known whether isotretinoin passes into breast milk. Do not take Tretizen 20 mg (Isotretinoin capsules) without first consulting your doctor if you are breast-feeding a baby.

Expert advice

  • Do not take isotretinoin, if you are allergic to isotretinoin, vitamin A or any other ingredients of the capsule.
  • Follow adequate contraceptive measures while on treatment with oral or topical isotretinoin.
  • Do not use if you are planning to become pregnant, already pregnant or breast feeding.
  • Women must use at least two methods of contraception while using isotretinoin to avoid becoming pregnant. Even men receiving isotretinoin must use contraception.
  • Do not take vitamin A supplements with isotretinoin.
  • Use sunscreen to protect skin from sunlight and UV rays (like sunlamps or tanning beds) while on isotretinoin treatment.
  • Do not use waxing for hair removal or do any dermabrasion or lazer skin treatments while on therapy with isotretinoin.
  • Do get your blood lipid levels, liver function, blood cell count and pregnancy test done before starting isotretinoin.
  • Do not donate blood till 30 days have passed after last capsule is taken.

Side Effects

  • Dry lips and mouth, minor swelling of the eyelids or lips, crusty skin, nosebleeds, upset stomach, or thinning of hair may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
  • To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.
  • Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
  • Tell your doctor right away if you have any of these unlikely but serious side effects: mental/mood changes (e.g., depression, aggressive or violent behavior, and in rare cases, thoughts of suicide), tingling feeling in the skin, quick/severe sunburn (sun sensitivity), back/joint/muscle pain, signs of infection (e.g., fever, persistent sore throat), painful swallowing, peeling skin on palms/soles.
  • Isotretinoin may rarely cause disease of the pancreas (pancreatitis) that may rarely be fatal. Stop taking this medication and tell your doctor right away if you develop: severe stomach pain, severe or persistent nausea/vomiting.
  • Stop taking this medication and tell your doctor right away if you develop these unlikely but very serious side effects: severe headache, vision changes, ringing in the ears, hearing loss, chest pain, yellowing eyes/skin, dark urine, severe diarrhea, rectal bleeding.
  • A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Interactions

  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
  • Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: tetracyclines (e.g., minocycline, tetracycline), vitamin A-type drugs (e.g., acitretin, bexarotene), vitamin A, drugs that cause bone loss (e.g., anti-seizure drugs such as phenytoin, corticosteroids such as prednisone).
  • Tell your doctor when you start any new drug, and discuss if you should use additional reliable birth control. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well. (See also Warning section.)
  • This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Frequently asked questions

 

  • Is isotretinoin effective? Can it be used for oily skin? Can it be used for mild acne and does it clear scars permanently?
  • Isotretinoin is effective when used for indication and at doses advised by the doctor. It should not be used merely to treat oily skin. It should not be used for mild acne but only for severe acne which has not responded to other treatment. It may not clear scars permanently.

 

  • How long can I use isotretinoin?
  • Isotretinoin has to be used for at least 4-6 weeks. Please follow the advice of the doctor regarding the duration of use and do not self-medicate or use for extended period of time.
  • Can isotretinoin be taken with milk?
  • Yes isotretinoin can be taken with milk.
  • Does isotretinoin cause weight gain/weight loss/hair loss/affect menstrual cycle?
  • Isotretinoin is not known to commonly cause weight gain/weight loss/hair loss/affect menstrual cycle.
  • Should isotretinoin be taken by pregnant women?
  • Isotretinoin should be not be used by pregnant women. Studies have shown that even with a single dose it is known to cause congenital defects in children. A woman should not get pregnant while on therapy with this drug and at least two forms of birth control must be used.
  • Can I take ibuprofen/ creatinine/ vitamins/ Tylenol (paracetamol)/ antibiotics with isotretinoin?
  • There are no known drug-drug interactions between isotretinoin and ibuprofen/ creatinine/ vitamins other than Vitamin A/ Tylenol (paracetamol). However, vitamin A used in addition to isotretinoin can cause vitamin A toxicity. Tetracycline antibiotics and isotretinoin may lead to increase in pressure in the fluid surrounding the brain and spinal cord. Doctor’s advice should be strictly followed about taking any medications along with isotretinoin.

 

  • Is isotretinoin same as tretinoin?
  • Isotretinoin and tretinoin are different from each other, but they are forms of vitamin A and have similar indications of use.

 

  • Is isotretinoin a permanent cure for acne?
  • Isotretinoin is effective for severe acne not responding to other treatment. It does prevent acne from returning for a long time after a single course. However, in few cases, acne may return or flare-up.

 

 

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