Paroxetine belongs to a group of drugs called selective- serotonin reuptake inhibitors (SSRIs). It works by increasing the level of the chemical serotonin in the brain, which is usually decreased in depression and related diseases.

WHAT IS PAROXIT SR 12.5 MG (PAROXETINE)?

Paroxetine is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Paroxetine affects chemicals in the brain that may be unbalanced in people with depression, anxiety, or other disorders.

Paroxetine is used to treat depression, obsessive-compulsive disorder, anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).

The Brisdelle brand of paroxetine is used to treat hot flashes related to menopause. Brisdelle is not for treating any other conditions.

Paroxetine may also be used for purposes not listed in this medication guide.

WHAT IS IMPORTANT INFORMATION FOR PAROXIT SR 12.5 MG (PAROXETINE)?

You should not use paroxetine if you are also taking pimozide or thioridazine, or if you are being treated with methylene blue injection. Do not start or stop taking this medicine during pregnancy without your doctor’s advice.

Do not use paroxetine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.

Do not give paroxetine to anyone younger than 18 years old without the advice of a doctor. This medicine is not approved for use in children.

BEFORE TAKING PAROXIT SR 12.5 MG (PAROXETINE)

YOU SHOULD NOT USE THIS MEDICINE IF YOU ARE ALLERGIC TO PAROXETINE, OR IF:

• you are also taking pimozide or thioridazine; or
• you are being treated with methylene blue injection.

Do not use an MAO inhibitor within 14 days before or after you take paroxetine. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. After you stop taking paroxetine you must wait at least 14 days before you start taking an MAO inhibitor.

TO MAKE SURE PAROXETINE IS SAFE FOR YOU, TELL YOUR DOCTOR IF YOU HAVE:

• heart disease, high blood pressure, history of stroke;
• liver or kidney disease;
• a bleeding or blood clotting disorder;
• seizures or epilepsy;
• bipolar disorder (manic depression), or a history of drug abuse or suicidal thoughts;
• narrow-angle glaucoma; or
• low levels of sodium in your blood.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Taking an SSRI antidepressant during pregnancy may cause serious lung problems or other complications in the baby. However, you may have a relapse of depression or other treated conditions if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking this medicine during pregnancy without your doctor’s advice.

Paroxetine can pass into breast milk and may harm a nursing baby. You should not breastfeed while using this medicine.

Do not give paroxetine to anyone younger than 18 years old without the advice of a doctor. This medicine is not approved for treating depression in children.

HOW SHOULD I TAKE PAROXIT SR 12.5 MG (PAROXETINE)?

Take paroxetine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Do not stop using paroxetine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using paroxetine. Follow your doctor’s instructions about tapering your dose.

Store at room temperature away from moisture, heat, and light.

WHAT HAPPENS IF I MISS A DOSE FOR PAROXIT SR 12.5 MG (PAROXETINE)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.

WHAT HAPPENS IF I OVERDOSE FOR PAROXIT SR 12.5 MG (PAROXETINE)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of paroxetine can be fatal.

WHAT SHOULD I AVOID WHILE TAKING PAROXIT SR 12.5 MG (PAROXETINE)?

Drinking alcohol can increase some of the side effects of paroxetine.

Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. Using an NSAID with paroxetine may cause you to bruise or bleed easily.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

WHAT IS COMMON SIDE EFFECTS FOR PAROXIT SR 12.5 MG (PAROXETINE)?

WHAT IS EXPERT ADVICE FOR PAROXIT SR 12.5 MG (PAROXETINE)?

FREQUENTLY ASKED QUESTIONS FOR PAROXIT SR 12.5 MG (PAROXETINE)

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DISCLAIMER FOR PAROXIT SR 12.5 MG (PAROXETINE).