ZUDENA 100 MG (UDENAFIL)
- Zudena 100mg Udenafil is a drug used in urology to treat impotence. It belongs to a course of medicines called PDE5 prevention, which many various other erectile dysfunction medications such as avanafil, sildenafil, tadalafil, and vardenafil also come from.
- It was created by Dong-A Drug and is marketed under the trade name Udzire. With a maximum blood plasma focus reached after 1.0 to 1.5 hrs and a half-life of 11 to 13 hrs (a relatively rapid start and a long period of time of activity), both on-demand, as well as once-daily use udenafil, have been reported.
- Typical doses are 100 and 200 mg. Udenafil is available in Korea, Russia, and the Philippines; in the USA, it is not approved for usage UNITED STATE Food and Drug Administration.
- Erectile dysfunction (ED) is a lack of ability to achieve or sustain an erection ideal for sexual intercourse. Sexologists claim at least 10% of men in India might have to utilize these medications at some time.
- Research studies have shown that 40% of guys up to the age of 40 years have actually ED and also it rises 70% by 60 years.
- The typically suggested medications for the disorder in India are sildenafil( Viagra) and also tadalafil, which comes from a classification called phosphodiesterasetype5 drugs.
- Currently, Zydus, a pharmaceutical business, has actually got special consent to sell udenafil.
- Erectile dysfunction (ED) is a failure to attain or maintain an erection ideal for sexual intercourse. Sexologists say a minimum of 10% of males in India might need to make use of these medicines at some point.
- Researches have revealed that 40% of guys up to the age of 40 years have actually ED and it rises 70% by 60 years Udenafil has a trading name Udzire.
1 TABLET CONSISTS OF 100 MG OF ZUDENA 100 MG (UDENAFIL);.
There are one or four tablet computers per pack.
Udzire greatly enhances erection and the opportunity for successful sexual intercourse. The action of the medicine has an optimal duration – up to twenty-four hrs. The impact appears half an hour after taking the drug in the visibility of sexual stimulation.
MEDICINAL GROUP FOR ZUDENA 100 MG (UDENAFIL).
- Regulators potency.
THE MAKE-UP AND ALSO THE FORM ZUDENA 100 MG (UDENAFIL).
Tablet computers, film-coated udenafil 100 mg, Adjuvants: lactose, maize starch, colloidal silicon dioxide; L-hydroxypropylcellulose, hydroxypropyl-LF; talc, magnesium stearate, Coat: hydroxypropyl methylcellulose, talc, iron oxide red, iron oxide yellow, titanium dioxide, plans red stripes 1, 2 or 4 pieces.; in a container pack 1 (for 1 or 4 pcs.) or 2 (for 2 pcs.) product packaging. Covered tablet computers light pink color with a tinted yellow, oval imprinted with the symbol “100” on one side and signs in the form of letters “Z” and “Y”, risk-sharing – on the other. At the break – a white or nearly white.
WHAT IS MEDICINAL ACTIVITY FOR ZUDENA 100 MG (UDENAFIL)?
- Enhances erectile function.
WHAT IS INDICATIONS FOR ZUDENA 100 MG (UDENAFIL)?
Therapy of erection conditions, characterized by the lack of ability to accomplish or maintain penile erection sufficient for acceptable sexual intercourse.
WHAT IS PHARMACOKINETICS FOR ZUDENA 100 MG (UDENAFIL)?
Oral udenafil is rapidly absorbed as well as produces a result in 30-90 minutes (generally – 60 mins). Udenafil half-life is 12 hrs, due to the high binding to plasma healthy proteins (93.9%) effective period expands approximately 1 day after getting a single dosage. Alcohol, as well as food, have no effect on udenafil absorbability. Consuming alcohol at 112 ml (equivalent to 40% ethyl alcohol) in combination with dental udenafil a dose of 200 mg does not impact the pharmacokinetic profile of udenafil. Udenafil does not build up in the body, even continual intake does not produce significant modifications in its pharmacokinetics.
WHAT IS PHARMACODYNAMICS FOR ZUDENA 100 MG (UDENAFIL)?
- Udenafil is a selective relatively easy-to-fix inhibitor of details phosphodiesterase type 5-the (PDE-5), which advertises the metabolic rate of cyclic guanosine monophosphate (cGMP).
- Udenafil no direct relaxing result on separated corpus cavernosum, yet enhances sexual stimulation relaxing impact of nitric oxide by preventing PDE-5, in charge of the malfunction of cGMP in the spacious body.
- The result is a relaxation of smooth muscular tissues of arteries as well as blood circulation to the cells of the penis that triggers erections.
- The medicine has no result in the lack of sexual stimulation. Study artificial insemination revealed that udenafil is a careful inhibitor of the enzyme PDE-5.
WHAT IS CONTRAINDICATIONS FOR ZUDENA 100 MG (UDENAFIL)?
Hypersensitivity to any type of part of the medication; synchronized function of nitrates and also another benefactor of nitric oxide.
WHAT IS SAFETY MEASURES FOR ZUDENA 100 MG (UDENAFIL)?
- people with unrestrained arterial high blood pressure (high blood pressure > 170/100 mm Hg. st), hypotension (BP <90/50 mm Hg. Art.) individuals with hereditary degenerative illness of the retina (including retinitis pigmentosa, proliferative diabetic retinopathy);
- visibility of a congenital disorder of QT prolongation or rise of the QT interval as a result of taking the drugs; tendency to priapism;
- patients with physiological contortion of the penis; visibility of penile dental implant;
- during sexual activity in people with cardio system, as unsteady angina or angina taking place throughout sexual intercourse, persistent cardiac arrest (II-IV practical course according to the category NYHA),
- progressed in the past 6 months, uncontrolled cardiac arrhythmia – need to consider the potential threat for problems;
- while receiving of udenafil and also CCBs, alpha-blockers or other hypotensive drugs – may note the extra decrease in SBP and DBP by 7-8 mmHg.
- The item is not planned for usage in kids and also teenagers under the age of 18 years.
- Application of maternity and breastfeeding.
- According to the signed-up indication, the medication is not intended for usage in women.
ADVERSE EFFECTS OF ZUDENA 100 MG (UDENAFIL).
Palpitations, prolonged erections, flushing, dizziness eye discomfort, boosted lacrimation, nasal blockage, headache. There is no research for its adverse effects for men over 71 y.o. There are no adverse effects on sperm’s high quality.
IF YOU OVERDOSE FOR ZUDENA 100 MG (UDENAFIL)?
Signs and symptoms: with a single dose of the drug in a dose of 400 mg of adverse events were comparable to those observed when obtaining udenafil at reduced dosages but occurred a lot more frequently. Treatment: symptomatic. Dialysis does not speed up the elimination of udenafil.
APPLICATION AS WELL AS ADMINISTRATION FOR ZUDENA 100 MG (UDENAFIL).
Inside, regardless of the dish. Recommended dose- 100 mg, taken 30 minutes before prepared for the sexual task. The dosage may be increased to 200 mg offered specific efficiency and tolerability. The optimum suggested the regularity of application – 1 time per day.
SHELF-LIFE MEDICATION ZIDENA ®/ UDZIRE.
STORAGE CONDITIONS ZIDENA ®/ UDZIRE.
In dry, dark location at temperature levels not over 30 ° C.