Hormones area unit chemical agents, transmitters among totally different tissues of our organism. Hormones are produced by the endocrine glands. For example, sex hormones are produced mainly by ovaries and in insignificant quantity by adrenal glands. Hormones penetrate within the blood and create a targeted organ begin its operate activity or stop its work. The blood contains an oversized amount of assorted biologically active agents at a similar time, however, different hormones find their targeted organs. How it is going on?
There is a novel mode of action for all hormones, allowing them to know the targeted organs: hormones communicate with the specific albuminous molecules in the tissues, then penetrate into cells, and that means the process is started. It is fascinating that every secretion has own specific protein-receptor.
So, this system works on the lock-and-key principle where the hormones are keys, and the receptors are locks. It is evident that if ANy hormones aren’t made in an organism, corresponding “locks” could not be opened anymore and activity of this hormone-dependable organ will be decreased. For example, the estrogen receptors (female sex hormones) are situated practically in all tissues and organs, including the skin and the brain, thence, when sufficient quantity of estrogens is not synthesized not solely privates organs area unit modified, but other bodies. Ovaries area unit accountable for traditional operate of the feminine system.
However, ovaries activity is subordinated to the influence of ductless gland hormones, follicle-stimulating hormones (FSH) and luteinizing hormones. The coordinated work of ductless gland and ovaries is consummated on the principle of feedback, which means the low sex hormones level ends up in creating ovaries to supply a lot of hypophyseal hormones (follicle-stimulating and luteinizing hormones level is increased). Consequently, the sufficient estrogen level is accompanied by decrease in follicle-stimulating and luteinizing hormones.
As we’ve already known that gonad failure ends up in deficiency of estrogens, we can assume that in menopause level of these hypophyseal hormones will be significantly increased. This reality for the doctors is very important since it permits to seek out out that menstruum stops due to lack of follicles indicating at climacteric, or certain diseases. We stop our rationalization at now as a result of we have a tendency to don’t study diseases here.
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