Nowadays, many thousands of medicines for various diseases treatment square measure used worldwide. Despite well-tried potency and safety of those medicine, they will cause some uncommon reactions.
Thus, 15% of all side effects of drug therapy are allergic reactions.
Several types of drugs provoke allergic reactions more than any other drugs do, these are:
- Antibiotic substances (up to 55%)
- Nonsteroidal anti-inflammatory drugs (up to 25%)
- Sulfanilamides (up to 10%)
- Vaccines, vitamins, enzymes (up to 10%)
Allergic reaction to antibiotics could be a natural reaction of the body to medication or its metabolites. The severity and frequency of hypersensitivity rely upon dose of antibiotics and time individuals use them.
Usually, a single or preventive application of antibiotics does not cause side effects. A long-term parenteral use of high doses of antibiotics (like injections) increases the risk of allergic reaction.
The majority of allergic reactions to antibiotics have similar signs:
- Occur in small number of people
- Develop quickly in repeated administration of an allergen
- Appear when using antibiotics with identical chemical structure
If a patient has aversion to antibiotics, he ought to stop exploitation the drug and confirm the reason for this reaction. Hypersensitivity to antibiotics happens either on the active pharmaceutical ingredient, or on excipients. If aversion is caused by the active substance, then you need to use other antibiotic.
If doctor finds out that aversion was caused by excipients, then you can buy and use some similar antibiotic drug by other pharmaceutical company. Typically, antibiotics manufacturers use different excipients. You can find the list of excipients in the leaflet.
It ought to be noted that frequent recurrent antibiotic therapies increase the chance of aspect effects and hypersensitivity. If you’re sensitive to numerous allergens, you can buy antibiotics for a short-term therapy. Such medications rarely cause side effects.
Distributors of antibiotics provide same medications in several pharmaceutical forms. The safest pharmaceutical styles of antibiotics ar tablets or capsules. Local application or parenteral route of administration of antibiotics increases the risk of adverse reactions.
There are risk factors of allergic reactions that do not depend on the type of used antibiotics. These factors ar age, sex and constitution peculiarities (for instance, leanness). It must be said that drug allergy is milder and less harmful in elderly and children.
Antibiotics effects could vary from delicate hypersensitivity to severe and exhausting aspect effects. Treatment of aversion to antibiotics ought to be started once the primary signs and symptoms occur.
Hypersensitivity to antibiotics, as well as allergy to other medications can be determined according to Gell and Coombs classification. In some cases, symptoms of allergy may be dangerous for health.
The most common allergic reaction to antibiotics is usually one of the listed below:
- Rash, irritated skin, blisters
- Anaphylactic shock
- Drug fever
- Low blood pressure
- Edema and narrowing of the larynx
As well as other medications, antibiotics are not recommended for use during pregnancy. Except for the cases when it is a necessity. Allergic reaction to antibiotics throughout maternity is usually constant in ladies, who are pregnant and who are not, yet it can be stronger.
One of the most common causes of antibiotic intolerance is considered penicillin. Antibiotics of this sort need a special attention attributable to their quality. In fact, penicillin causes side effects and leads to hospitalization more often than any other antibiotic drugs.
If you employ antibiotics from time to time and you’re allergic to antibiotic, you must be aware what drugs you can take. Obviously, you should not buy antibiotics which name contains ‘Penicillin’ word.
At the USA pharmacies, you can buy several antibiotics which name has ‘Penicillin’ in it – Penicillin-Vk, Penicillin G Potassium, Penicillin G Sodium and others. The UK pharmacies offer to buy Penicillin-Vk (tablets and capsules) and Phenoxymethylpenicillin (granules for oral solution).
Antibiotics containing active substance antibiotic are offered below whole names containing no word ‘Penicillin’ (for example, Amoxicillin, Cilicaine Syringe, Bicillin, Penapar and V-Cillin). You may find the information on substances of the drugs in the leaflet.
Allergic reaction to antibiotics usually happens if medication ar used improperly. To maximally reduce the risk of adverse reactions,
you should follow some simple recommendations:
- If you have no idea what infection a particular antibiotic is meant for, do not use it
- Learn side effects of antibiotics and take precautions
- Use antibiotics in recommended doses only (no less, no more)
- Continue using antibiotics until you are completely healthy
If antibiotics pills cause allergic reaction – eruption, itching, troublesome respiration or another serious reaction, an individual ought to stop mistreatment it and ne’er take it once more. Use antibiotics only when strictly necessary.